Imitrex (Sumatriptan) is a prescribed migraine headache medication of the class known as the triptans. It is prescribed both for migraine and cluster headaches. It is not considered safe in pregnancy. The usual dose is 6mg subcutaneouls (just under the skin) which may be repeated 1 hour later. The maximum dose in 24 hours however is 12mg. It also comes as a nasal spray, the usual dose being one spray which may be repeated in 1 hour for a maximum of 2 sprays per day. It is prohibited in patients with ischemic heart disease or cerebrovascular disease (stroke or TIA) or peripheral vascular diseases including ischemic bowel disease. It is also prohibited in vasospastic coronary artery disease, uncontrolled hypertension, basilar or hemiplegic migraines or severe liver impairment. It is prohibited within 24 hours of ergot-type drugs (like methysergide or DHE) or other 5-HT agonist drugs. It has a variety of side effects, most significantly chest or jaw pain, colonic ischemia, and rarely serious cardiac events.

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