Imitrex (Sumatriptan) is a prescription medication of the class known as 5HT-1a receptor agonists. It is not considered safe in pregnancy but is considered safe in nursing. It is used for the treatment of migraine headaches and cluster headaches. The usual dose is 6mg subcutaneously by injection or 25-50mg orally, which may be repeated in 2 hours.
It should not be combined with MAOIs. It should not be given to patients with a history or symptoms of ischemic heart disease, stroke, or peripheral vascular disease. It should also not be given in patients with uncontrolled hypertension, or in patients with basilar or hemiplegic migraine. It should not be given within 24 hours of ergot-type drugs or another 5HT-1 agonist.
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