Bactrim (Trimethoprim-Sulfamethoxazole) is a prescribed antibiotic of the class known as sulfonamides. It is used for urinary tract infections, shigellosis, bronchitis, otitis media, prophylaxis and treatment of Pneumocystis carini pneumonia (PCP) in AIDS patients, traveler's diarrhea, or acute exacerbations of chronic bronchitis in adults. It is not considered safe in pregnancy, but is considered safe in nursing mothers. It is not to be used (contraindicated) in megaloblastic anemia due to folate deficiency (trimethoprim inhibits folic acid), patients (women) in their 3d trimester of pregnancy, infants or nursing mothers of ill, stressed, G6PD deficient, premature or hyperbilirubinemic infants. It may cause GI upset, allergic skin reactions (some can be severe), and a variety of blood dyscrasias and hemolysis.
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