Advair (Salmeterol & Fluticasone) is a prescribed medication in the class of long acting b- agonists. It is used for maintenance treatment of asthma and COPD with chronic bronchitis. The usual starting dose is 250/50 (250 micrograms of fluticasone, and 50 micrograms of salmeterol) every 12 hours. It is not used for the treatment of acute attacks. It is not considered safe in pregnancy or nursing. CYP3A4 inhibitors including certain antifungals, antivirals, erythromycin, and grapefruit juice can significantly increase fluticasone concentrations causing systemic effects, including adrenal suppression. Do not abruptly stop therapy.
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